UK Clinical Trial Confirms Breakthrough Treatment for COVID-19
- VANCOUVER, British Columbia & SURREY, England–(BUSINESS WIRE)–Biotech company SaNOtize Research & Development Corp., (SaNOtize), Ashford and St Peter’s Hospitals NHS Foundation Trust in Surrey, UK, and Berkshire and Surrey Pathology Services, UK, today announced results of clinical trials indicating that SaNOtize’s Nitric Oxide Nasal Spray (NONS) represents a safe and effective antiviral treatment that could prevent the transmission of COVID-19, shorten its course, and reduce the severity of symptoms and damage in those already infected.
- Patients with a self-administered nasal spray application found to have reduced SARS-CoV-2 viral load by more than 95% in infected participants within 24 hours of treatment, and by more than 99% in 72 hours
- Trial concluded that treatment accelerated clearance of SARS-CoV-2 by a factor of 16-fold versus a placebo
- Randomized, double-blind, placebo-controlled trial evaluated 79 confirmed cases of COVID-19, the majority heavily-infected with the UK variant
- No adverse events were recorded in the group
- Submission for Emergency Use in the UK and Canada for the treatment and prevention of COVID-19 is planned immediately
In a randomized, double-blind, placebo-controlled Phase 2 trial that evaluated 79 confirmed cases of COVID-19, SaNOtize’s early treatment for COVID-19 significantly reduced the level of SARS-CoV-2, including in patients with high viral loads. The average viral log reduction in the first 24 hours was 1.362, which corresponds to a decline of about 95%. Within 72 hours, the viral load dropped by more than 99%. The majority of these patients had been infected with the UK variant, which is considered a variant of concern. There were no adverse health events recorded in the UK trial, or in over 7,000 self-administered treatments given in earlier Canadian clinical trials.
NONS is the only novel therapeutic treatment so far proven to reduce viral load in humans that is not a monoclonal antibody treatment. Monoclonal antibodies are highly specific, expensive and must be administered intravenously in a clinical setting.
“I expect this to be a major advance in the global battle against the devastating human impacts of the COVID-19 pandemic,” said Dr. Stephen Winchester, Consultant Medical Virologist and Chief Investigator of this NHS Clinical Trial. “This simple portable nasal spray could be highly effective in the treatment of COVID-19 and reducing onward transmission. Our trial included patients with a variant of concern and high viral loads yet still demonstrated significant reductions in the levels of SARS-CoV-2, which could be critical in supporting vaccines, preventing future outbreaks and safely reopening economies. Simply stated, I think this could be revolutionary.”
The SaNOtize treatment is designed to kill the virus in the upper airways, preventing it from incubating and spreading to the lungs. It is based on nitric oxide (NO), a natural nanomolecule produced by the human body with proven anti-microbial properties shown to have a direct effect on SARS-CoV-2, the virus that causes COVID-19. The pharmacology, toxicity, and safety data for NO use in humans has been well-established for decades. The NO molecule released from NONS is identical to the one delivered in its gaseous form to treat persistent pulmonary hypertension, or Blue Baby Syndrome, in newborn babies.
SaNOtize Seeking Emergency Use Authorization in UK and Canada
SaNOtize is applying to regulatory authorities in the UK and Canada for Emergency Use authorization. Swift approval and ramp-up of manufacturing could facilitate an almost immediate safe return to work, school and society, and spur an economic recovery that is months – if not years – ahead of full global vaccination.
Wide-scale equitable global availability of NONS could form a bridge during the global production and distribution of vaccines to help keep people safe and healthy. The ease of NONS manufacture, storage and use makes NONS a treatment candidate that could soon be widely available at low-cost for long-term care facilities, healthcare and frontline workers, and the general population.
In addition to providing antiviral treatment in the early stages of infection and for those who have yet to be vaccinated, NONS has also demonstrated that it could also reduce infectivity – the frequency of transmission from an infected person to a non-infected person.
The results of the UK trial corroborate the information gathered from SaNOtize’s earlier Phase 2 trials in Canada and independent lab tests at Utah State University’s Antiviral Research Institute.
“Now that NONS has been demonstrated to be safe and effective in clinical trials, we must move with urgency to get it into the hands of the public where it can help bring an end to the pandemic, accelerate a return to normality, and prevent future outbreaks of COVID-19 and its variants,” said Dr. Gilly Regev, CEO and co-founder of SaNOtize. “The human toll of this disease cannot be expressed simply in numbers, and each day compounds the frustration, fear and loss suffered by millions around the world. Combined with the roll-out of vaccines, NONS can help get the world back on its feet
-from David Blake
Queensland
Why pay for something when you can do it all for free – you buy Saxa Salt (or any other salt from your supermarket) and use that with warm tap water – you see what you use, how hard can that be?
Coronavirus and viruses cure:
1 heaped teaspoon of salt in a mug of warm water, (can be cold) cup a hand and sniff or snort the whole lot up, spitting anything which comes down into your mouth – no reaction fine, blow out your nose, flush away, washing your hands afterwards, you don’t have a virus .
A reaction, you have a virus – retain the salt water in your head for as long as the soreness lasts (2-3 minutes) then blow out your nose, flush away, washing hands afterwards and do this treatment 3 times a day, morning, noon, night, or more often, until the soreness goes away, when you have killed off the virus in your head and you won’t get the disease it will become, as I have done these past 26 years and to this, I add those virus related diseases which remain unknown to us, but are delivered by a virus, as in (unspecified) air pollution. Simple.
Me, 9,490 days never ill, salt water cure vs vaccines about 160 days and horrid side effects, The European Union’s vaccine injury reporting system had logged 330,2018 adverse event reports, including 7,766 deaths, as of April 17, 2021, and the U.S. reporting system had logged 118,902 adverse event reports as of April 23, including 3,544 deaths and 12,618 serious injuries (Mercola) it is a test vaccine and the makers cannot be held accountable for whatever it does, in the short, or longer term – you are human laboratory white mice, all said and done. Vaccinated. Too late!!
Try it, if you are satisfied with the results, pass the cure along, if results are not excellent, there are still the untested, trial vaccines to fall back on.
I never have Flu shots, or this vaccine either. No point doing the above salt water cure and then having vaccine shots too – like Duh!!
About 26 years ago, I read the report from a posh Research Center in America, where the author suggested, in his research paper, that his experiments with Salt Water cured flu type colds and he in turn referred to the Swedish or Norwegian Army (I think), who had barrels filled with Salt Water, attached to a hose, out of the bottom, which soldiers used to flush out their heads, when they thought they were getting a cold – and their troops never got colds.
I have been doing it ever since and neither do I, from any virus related “thing”.
There are weak salt water spray preparations you can buy from your local chemist, to clear your head. To my way of thinking, (as above) you need a stronger salt water solution to wash out your inner head and no spray is ever going to be enough to do that, which is proof of safety concerns, regarding salt, as above.
If you are allergic to salt – don’t do as I suggest!!
Richard
Reading this article makes me wonder what’s the odds that this type of nasal spray does not contain Nanoparticles that can alter your DNA as well. It’s scary the path we need to travel to to have normal lives that is not manipulated by our Governments and our Health Care system.
Probably because you inhale your Asthma medication by using your mouth, well at least I do, not you nose at all and with the Coronavirus in your head, accessing your head, by your nose, into the wet, warm, humid areas of your head, where coronavirus strips the skin off the flesh, which lines your inner skull and begins its development into Covid from there – breathing in your Asthma shot into your mouth, which goes down your throat into your lungs, releasing any breathing bottlenecks there (pretty much instantaneously) is never going to deal with the Coronavirus infected sites in your upper head, as you can see.
I don’t see the big deal about sniffing or snorting salt water into your head to murder Coronavirus and any infection it has so far created, with a discomfort time of 2-3 minutes, each time you do it, until sniffing the salt water solution into your head, gives you no internal head discomfort reaction, when you have killed off Coronavirus until the next time you get an infection vs getting the Coronavirus and all of the symptoms for 10 to 14 days, of bed ridden misery, to discover you now have Covid and all of the pleasures of that, including your 2 test vaccine shots “to save your life” instead.
At least, I am trying to save your life, for the rest of your life, for free – against the free, paid test vaccine versions, which cause more problems than they save, it seems to me and over 26 years plus (9,500 days) of my personal testing on my body to prove my salt water treatment has kept me safe and will continue to do so, is fully tested and self proven – against vaccines made available since 8th December 2020 – what is that, roughly 150 days?
Do the math.
Richard
Why do they not compare it to common asthma inhalant Budesonide.
You can of course buy salt based nasal sprays from your local chemist, which do what this nasal spray might do, but, to my way of thinking, they fall far short of stopping Coronavirus from becoming Covid, which is what my simple salt water sniffle does for free.
Richard
Forget nasal spray – that does not flush Coronavirus out of your head, or from around your brain bulb, or brain stem, or kill it, when it inserts itself in the fleshy areas in the warm, wet, humid areas, inside your head, which my salt water sniffle does and you will discover why, when you do your salt water sniffle and discover the hole, roughly level with your ears, which the 1 liter of mucus or snot, we each produce daily (the engine oil of the body) goes into your throat through and that is a good place to find that it is sore, when the rest of your head is not, but that said and done, it is otherwise what I have been suggesting on these pages for some months now, however, the biggest bonus being my salt water cure won’t cost you anything and you can mix it up from water and salt and do it in your own home, whenever you feel you “might” have caught something you don’t want.
Richard.
Thats GREAT NEWS Big thanks.Now try to convince the Oz Gov?
They won’t let it get to the market not enough stupid peer reviews or Blah Blah Blah someway they will block it, the same as Hydrocyhloroquine and Zinc or Ivermectin Doxycycline and Zinc 51 reviews and reports on Ivermectin but it’s still a no show in Australia Professor Thomas Borody must be banging on his desk and shaking his head, but if the people keep taking these jabs they will soon be dead especially with the Pfizer and Moderna mRNA ones while the others will cause more decease and blood 🩸 clots etc 😎👍🥋